Eukaryotic Gene Expression - basics and benefits


Lecture 1 - Eukaryotic RNA polymerases and basal transcription factors


Lecture 2 - Diversity in core promoter elements


Lecture 3 - Diversity in general transcription factors


Lecture 4 - Proximal & Distal Promoter Elements, Enhancers and Silencers, Gene-specific Regulators


Lecture 5 - Transcription factors - DNA binding domains


Lecture 6 - Transcription factors - Transcription activation domain


Lecture 7 - Role of chromatin in eukaryotic gene regulation


Lecture 8 - Role of histones in eukaryotic gene regulation


Lecture 9 - Role of DNA methylation in eukaryotic gene regulation


Lecture 10 - Chromatin remodelling & gene regulation


Lecture 11 - mRNA processing - Role of RNA Pol II in mRNA capping and mRNA splicing


Lecture 12 - mRNA processing - Role of RNA Pol II in polyadenylation & mRNA editing


Lecture 13 - Regulation of RNA Pol I transcription


Lecture 14 - Regulation of RNA Pol III transcription


Lecture 15 - Signal Transduction Pathways - Introduction


Lecture 16 - Regulation of gene expression by cyclicAMP


Lecture 17 - Regulation of gene expression by second messengers other than cAMP


Lecture 18 - Regulation of gene expression by Protein Kinase C


Lecture 19 - Regulation of gene expression by Growth factors


Lecture 20 - Regulation of gene expression by cytokines


Lecture 21 - Regulation of gene expression by steroid hormones


Lecture 22 - Regulation of gene expression by type II nuclear receptors


Lecture 23 - Mechanism of transcriptional activation by nuclear receptors


Lecture 24 - Gene Regulation during Drosophila Development


Lecture 25 - Signal transduction pathways involved in embryonic development


Lecture 26 - Homeotic genes


Lecture 27 - Epigenetic regulation of gene expression during development


Lecture 28 - Embryonic stem cells and Transcription factor-mediated epigenetic reprogramming


Lecture 29 - Cloning and Expression vectors


Lecture 30 - Eukaryotic protein expression systems - I


Lecture 31 - Eukaryotic protein expression systems - II


Lecture 32 - Eukaryotic protein expression systems - III: Gene expression in mammalian cells using viral vectors


Lecture 33 - Human Gene Therapy


Lecture 34 - DNA vaccines


Lecture 35 - Transgenic animals


Lecture 36 - Transgenic plants


Lecture 37 - Knockout mic


Lecture 38 - Regulation of Eukaryotic Gene Expression by Small RNAs (RNA Interference, RNAi)


Lecture 39 - Genomics & Proteomics


Lecture 40 - Metabolic Engineering & Synthetic Biology